If you’ve been following the latest developments in weight management, you’ve probably heard about the new generation of weight loss medications. While injectable treatments such as Wegovy® and Mounjaro® have become well known, many people are now asking about the recently launched weight loss tablets.
So, what are the differences, and could tablets be the right option for you?
Why are these medications so popular?
Obesity is a complex medical condition that affects millions of people in the UK and increases the risk of developing type 2 diabetes, heart disease, high blood pressure, sleep apnoea and certain cancers.
Modern weight loss medications work by targeting the body’s natural appetite hormones. Rather than relying on willpower alone, they help people feel fuller for longer, reduce hunger, and make it easier to eat smaller portions. When combined with healthy lifestyle changes, they can help achieve meaningful and sustained weight loss.
The Weight Loss Injections
The injectable medications are taken once a week using a small injection pen.
These medicines have shown impressive results in clinical studies, with many people losing between 15% and over 20% of their starting body weight, depending on the medication, dosage and individual response. They are generally considered the most effective medical treatments currently available for obesity.
What About the New Tablets?
A significant recent development is the introduction of oral weight loss tablets. These contain the same active ingredient some injections, but are taken as a once-daily tablet rather than a weekly injection. The first tablet specifically approved for weight management has recently become available, giving patients another treatment option.
For many people, taking a tablet may feel less daunting than giving themselves a weekly injection. However, tablets need to be taken exactly as directed, often first thing in the morning on an empty stomach with a small amount of water, before eating or drinking anything else.
While the tablets can produce significant weight loss, current evidence suggests that the weekly injections may still achieve greater average weight loss for many patients.
Which Treatment is Better?
There isn’t a single “best” option—it depends on the individual.
An injectable treatment may be more suitable if:
- You’re looking for the greatest potential weight loss.
- You prefer a once-weekly medication.
- You’re comfortable with self-injection.
A tablet may be a good option if:
- You dislike injections.
- You prefer taking medication by mouth.
- You’re happy to follow the daily dosing instructions carefully.
Your healthcare professional will consider factors such as your BMI, medical history, existing health conditions, current medications and your personal preferences before recommending a treatment.
Are There Side Effects?
Like all medicines, weight loss medications can cause side effects.
The most common include:
- Nausea
- Vomiting
- Diarrhoea
- Constipation
- Indigestion
- Reduced appetite
These symptoms are usually mild and tend to improve as your body adjusts to the medication. Starting on a low dose and gradually increasing it helps reduce the risk of side effects.
Although uncommon, serious side effects can occur, so it’s important to seek medical advice if you experience severe abdominal pain, persistent vomiting, or any concerning symptoms.
Medication Isn’t a Magic Solution
One of the biggest misconceptions is that these medicines “do all the work.”
In reality, they work best alongside:
- A balanced, nutritious diet
- Regular physical activity
- Good sleep habits
- Behavioural and lifestyle changes
- Ongoing support from healthcare professionals
The medication helps reduce hunger, but long-term success comes from developing healthier habits that can be maintained over time.
Who Can Have Weight Loss Medication?
These medications are prescription-only and are not suitable for everyone.
They are generally considered for adults living with obesity or those who are overweight and have weight-related health conditions. A healthcare professional will assess whether the treatment is appropriate and safe for you.
The Bottom Line
The arrival of weight loss tablets is an exciting development, giving patients more choice than ever before. While weekly injections remain the most effective option for many people, tablets provide an excellent alternative for those who prefer not to inject.
The most important thing to remember is that successful weight management is about finding the right treatment for you. Whether that’s injections, tablets, lifestyle support, or a combination of approaches, the goal is to improve your long-term health—not just the number on the scales.
If you’re interested in learning more about weight loss treatments, speak to our clinical team. We’ll discuss your goals, review your medical history, and help you decide whether medication could form part of your personalised weight management plan.